Skunk Supreme marijuana is a cross between Super Skunk & Critical which will create a relaxing effect over the body, which makes it the perfect answer for your stress and body pains. You can use Skunk Supreme all times of day for pain relief. Use it at night to calm anxiety and alleviate insomnia. People with headaches and cramps also use Skunk Supreme. For recreational users, Skunk Supreme is something to get excited about as it may put you into a spacey state or a euphoric zone.